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GMC Sierra 2500 HD Engine Coolant Thermostat Replacement

1
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  1. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 267-195

    195 Degrees F Includes Seal OE Specified Temperature

    $12.21 View part →
  2. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 267-180

    180 Degrees F Includes Seal Alternate Temperature Option

    $12.21 View part →
  3. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 267-160

    160 Degrees F Includes Seal Alternate Temperature Option

    $12.21 View part →
  4. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 2067-180

    180 Degrees F Includes Seal Alternate Temperature Option

    $12.26 View part →
  5. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 2067-195

    195 Degrees F Includes Seal OE Specified Temperature

    $12.26 View part →
  6. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    Partslink #: W0133-3408446
    $13.85 View part →
  7. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH6470.82J

    Replaces TH6470.82 With By-pass valve; Gasket Included Opening Temp: 82 C / 180 F Aftermarket Alternative

    $15.59 View part →
  8. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH6470.71J

    Replaces TH6470.71 With gasket / seal Opening Temp: 71 C / 160 F Aftermarket Alternative

    $15.59 View part →
  9. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH6470.91J

    Replaces TH6470.91 With By-pass valve; Gasket Included Height: 2.12 in Opening Temp: 91 C / 196 F Aftermarket Alternative

    $15.59 View part →
  10. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 5267-195

    195 Degrees F Includes Seal OE Specified Temperature

    $15.93 View part →
  11. ✓ In Stock 2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    Partslink #: W0133-3372355
    $17.24 View part →
  12. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: THF6470.91J

    High Flow Thermostat; Gasket Included Opening Temp: 91 C / 196 F Aftermarket Alternative

    $17.67 View part →
  13. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 7267-180

    180 Degrees F Includes Seal Alternate Temperature Option ; "The patented Fail-Safe (R) thermostat is the only thermostat on the market designed to lock in the open position, allowing coolant to continue to flow in the event of overheating."

    $17.97 View part →
  14. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 7267-195

    195 Degrees F Includes Seal OE Specified Temperature ; "The patented Fail-Safe (R) thermostat is the only thermostat on the market designed to lock in the open position, allowing coolant to continue to flow in the event of overheating."

    $17.97 View part →
  15. ✓ In Stock 2001-2024 GMC Sierra 2500 HD Engine Coolant Thermostat - Rear (Motorad)

    2001-2024 GMC Sierra 2500 HD Engine Coolant Thermostat - Rear (Motorad)

    Partslink #: 448-180

    180 Degrees F Includes Seal OE Specified Temperature

    $18.12 View part →
  16. ✓ In Stock 2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH2105.86J

    Replaces THN1017 With jiggle-pin; With off-set valve seat; With leak holes on the bypass valve; Gasket included Opening Temp: 86 C / 187 F OEM Recommended With OE No. 12600171

    $18.73 View part →
  17. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 5456-187

    187 Degrees F Includes Seal with Replacement Late Model Water Pump Requiring Seperate Thermostat and Housing; Thermostat Only OE Specified Temperature

    $19.11 View part →
  18. ✓ In Stock 2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH2107.86J

    Replaces THN0755 With inversed jiggle-pin; Gasket included Opening Temp: 86 C / 187 F OEM Recommended With OE No. 89018168

    $20.19 View part →
  19. ✓ In Stock 2007-2024 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2007-2024 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 523-190

    187 Degrees F Includes Seal OE Specified Temperature

    $20.43 View part →
  20. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: 33329

    195 Degree; OE Temperature; Seal included

    $21.22 View part →
  21. ✓ In Stock 2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    Partslink #: W0133-3380375

    w/ 180°F

    $21.55 View part →
  22. ✓ In Stock 2001-2024 GMC Sierra 2500 HD Engine Coolant Thermostat - Front (Motorad)

    2001-2024 GMC Sierra 2500 HD Engine Coolant Thermostat - Front (Motorad)

    Partslink #: 447-185

    185 Degrees F Includes Seal OE Specified Temperature

    $21.65 View part →
  23. ✓ In Stock 2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat -  or Rear (Stant)

    2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat - or Rear (Stant)

    Partslink #: 14738

    Temperature 180 Degrees Seal Included - Seal OE Temperature This part is also available in the Engine Coolant Thermostat Kit 121KT, which contains 10248 (Radiator Cap), 14728 (Engine Coolant Thermostat) and 74040 (Engine Coolant Temperature Sensor)

    $22.24 View part →
  24. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 456-187

    187 Degrees F Includes Seal with Replacement Late Model Water Pump Requiring Seperate Thermostat and Housing; Thermostat Only OE Specified Temperature

    $23.19 View part →
  25. ✓ In Stock 2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 523-174

    174 Degrees F Includes Seal Alternate Temperature Option

    $23.19 View part →
  26. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 456-160

    160 Degrees F Includes Seal with Replacement Late Model Water Pump Requiring Seperate Thermostat and Housing; Thermostat Only Alternate Temperature Option

    $23.19 View part →
  27. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 456-180

    180 Degrees F Includes Seal with Replacement Late Model Water Pump Requiring Seperate Thermostat and Housing; Thermostat Only Alternate Temperature Option

    $23.19 View part →
  28. ✓ In Stock 2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: 33963

    Excludes Housing; 186 Degree; OE Temperature; Seal included

    $24.03 View part →
  29. ✓ In Stock 2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 523-180

    180 Degrees F Includes Seal Alternate Temperature Option

    $25.03 View part →
  30. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 7456-187

    187 Degrees F Includes Seal with Replacement Late Model Water Pump Requiring Seperate Thermostat and Housing; Thermostat Only OE Specified Temperature ; "The patented Fail-Safe (R) thermostat is the only thermostat on the market designed to lock in the open position, allowing coolant to continue to flow in the event of overheating."

    $27.27 View part →
  31. ✓ In Stock 2007-2024 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2007-2024 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: 34198

    190 Degree; OE Temperature; Seal included

    $28.37 View part →
  32. ✓ In Stock 2001-2018 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    2001-2018 GMC Sierra 2500 HD Engine Coolant Thermostat (Autopart International)

    Partslink #: W0133-3395887

    w/ 185°F

    $29.25 View part →
  33. ✓ In Stock 2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 523-160

    160 Degrees F Includes Seal Alternate Temperature Option

    $32.64 View part →
  34. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: 33329S

    195 Degree; OE Temperature; Seal included

    $33.93 View part →
  35. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH2105.71J

    With jiggle-pin; With off-set valve seat; With leak holes on the bypass valve; Gasket included Opening Temp: 71 C / 160 F Aftermarket Alternative

    $35.81 View part →
  36. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH2105.82J

    With jiggle-pin; With off-set valve seat; With leak holes on the bypass valve; Gasket included Opening Temp: 82 C / 180 F Aftermarket Alternative

    $35.85 View part →
  37. ✓ In Stock 2007-2018 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2007-2018 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: 34198S

    187 Degree; OE Temperature; Seal included

    $37.62 View part →
  38. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: W0133-1682422
    $39.16 View part →
  39. ✓ In Stock 2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    2007-2023 GMC Sierra 2500 HD Engine Coolant Thermostat (Motorad)

    Partslink #: 5523-187

    187 Degrees F Includes Seal OE Specified Temperature

    $41.96 View part →
  40. ✓ In Stock 2001-2003 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    2001-2003 GMC Sierra 2500 HD Engine Coolant Thermostat (Calorstat)

    Partslink #: TH7480.71J

    With integrated housing thermostat; Gasket Included Opening Temp: 71 C / 160 F Aftermarket Alternative

    $45.38 View part →
  41. ✓ In Stock 2001-2003 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2001-2003 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: 33910

    W/Original Equipment or Most Aftermarket Water Pumps; 186 Degree; OE Temperature; Seal included

    $47.23 View part →
  42. ✓ In Stock 2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    Partslink #: W0133-1694589
    $48.71 View part →
  43. ✓ In Stock 2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: W0133-1783286
    $53.45 View part →
  44. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    Partslink #: 131-131
    $56.76 View part →
  45. ✓ In Stock 2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    2004-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    Partslink #: W0133-1783286
    $61.25 View part →
  46. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    Partslink #: 131-163
    $61.59 View part →
  47. ✓ In Stock 2001-2016 GMC Sierra 2500 HD Engine Coolant Thermostat - Front (Gates)

    2001-2016 GMC Sierra 2500 HD Engine Coolant Thermostat - Front (Gates)

    Partslink #: 33946

    185 Degree; OE Temperature; Seal included

    $65.47 View part →
  48. ✓ In Stock 2001-2024 GMC Sierra 2500 HD Engine Coolant Thermostat - Cylinder Head (Motorad)

    2001-2024 GMC Sierra 2500 HD Engine Coolant Thermostat - Cylinder Head (Motorad)

    Partslink #: 447448

    180 Degrees F 185 Degrees F Includes Seal Kit Contains Front and Rear Thermostats OE Specified Temperature

    $65.80 View part →
  49. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    Partslink #: MMTS-VET-97L
    $68.95 View part →
  50. ✓ In Stock 2007-2022 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    2007-2022 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    Partslink #: MMTS-VET-05
    $68.95 View part →
  51. ✓ In Stock 2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat - Rear (Gates)

    2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat - Rear (Gates)

    Partslink #: 33947

    180 Degree; OE Temperature; Seal included

    $69.23 View part →
  52. ✓ In Stock 2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    2001-2019 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    Partslink #: W0133-1694074

    w/ 180°F

    $76.79 View part →
  53. ✓ In Stock 2007-2022 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    2007-2022 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    Partslink #: W0133-1821992
    $87.27 View part →
  54. ✓ In Stock 2001-2018 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    2001-2018 GMC Sierra 2500 HD Engine Coolant Thermostat (ACDelco)

    Partslink #: W0133-1694073

    w/ 185°F

    $94.40 View part →
  55. ✓ In Stock 2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    2001-2006 GMC Sierra 2500 HD Engine Coolant Thermostat (Gates)

    Partslink #: 34702

    Includes Housing; 187 Degree; OE Temperature; Seal included

    $96.38 View part →
  56. ✓ In Stock 2001-2021 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    2001-2021 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    Partslink #: MMTS-CHV-01DL
    $99.95 View part →
  57. ✓ In Stock 2001-2021 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    2001-2021 GMC Sierra 2500 HD Engine Coolant Thermostat (Mishimoto)

    Partslink #: MMTS-CHV-01DH
    $99.95 View part →

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Engine Coolant Thermostat Compatibility for GMC Sierra 2500 HD

Browse our selection of quality engine coolant thermostat parts designed specifically for your GMC Sierra 2500 HD. We carry options across multiple trim levels, body styles, and engine configurations to ensure a perfect fit.

Available Trims

AT4 · AT4X · Base · Denali · Denali Ultimate · Pro · SL · SLE · SLT · WT

Body Types

Crew Cab Pickup · Extended Cab Pickup · Standard Cab Pickup

Engine Options

V8 6.0L · V8 6.6L · V8 8.1L

Transmissions

Automatic · Manual

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